BM3251 BIOSCIENCES FOR MEDICAL ENGINEERING
Prepared by
S.Santhosh (Admin)
Important questions
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2. Clinical application of Electrolytes and radioisotopes.**
water as a biological solvent, weak acid and bases may be 2 marks askedin this topic
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UNIT -2
2.DNA,RNA full topic**
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2. Necrosis, Apoptosis, Intracellular accumulations, Pathological calcification**
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1.Hematological disorders- Bleeding disorders, Leukaemias, Lymphomas Haemorrhage.
2. RIA and ELISA, monoclonal antibodies
**Very important questions are bolded and may be asked based on this topic
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*These questions are expected for the exams This may or may not be asked for exams All the best.... from admin Santhosh
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SYllabuS
FUNDAMENTALS TO BIOCHEMISTRY
Introduction to Biochemistry, water as a biological solvent, weak acid and bases, pH, buffers, Handerson - Hasselbalch equation, physiological buffers in living systems, Energy in living organism. Properties of water and their applications in biological systems. Introduction to Biomolecules, Biological membrane, Clinical application of Electrolytes and radioisotopes.
UNIT IICARBOHYDRATES, LIPIDS, PROTEIN
Classification of carbohydrates - mono, di, oligo and polysaccharides. Structure, physical and chemical properties of carbohydrates - Classification of lipids- simple, compound, and derived lipids. Nomenclature of fatty acid - Structure and properties of proteins, structural organization of proteins, classification and properties of amino acids. Nucleic acid: Structural aspects – Components of DNA and RNA, Nucleosides & Nucleotides (introduction, structure & bonding), Double helical structure of DNA (Watson-Crick model), various forms of DNA.
UNIT IIICELL DEGENERATION, REPAIR AND NEOPLASIA
Cell injury - Reversible cell injury and Irreversible cell injury and Necrosis, Apoptosis, Intracellular accumulations, Pathological calcification- Dystrophic and Metastatic. cellular adaptations of growth and differentiation, Inflammation and Repair including fracture healing, Neoplasia, Classification, Benign and Malignant tumours, carcinogenesis, spread of tumours Autopsy and biopsy.
Edema, Hyperemia/Ischemia, normal hemostasis, thrombosis, disseminated intravascular coagulation, embolism, infarction, shock, Chronic venous congestion. Hematological disorders- Bleeding disorders, Leukaemias, Lymphomas Haemorrhage.
UNIT VFUNDAMENTALS OF MICROBIOLOGY AND IMMUNOPATHOLOGY Structure of Bacteria and Virus - Morphological features and structural organization of bacteria and virus - List of common bacterial, fungal and viral diseases of human beings.- Basics of Microscopes : Light microscope, Electron microscope (TEM & SEM). - Natural and artificial immunity, types of Hypersensitivity, antibody and cell mediated tissue injury, Immunological techniques: immune diffusion, immuno electrophoresis, RIA and ELISA, monoclonal antibodies